Mathematical, biological, and computational explanations
نویسندگان
چکیده
منابع مشابه
Mathematical and Computational Modeling in Complex Biological Systems
The biological process and molecular functions involved in the cancer progression remain difficult to understand for biologists and clinical doctors. Recent developments in high-throughput technologies urge the systems biology to achieve more precise models for complex diseases. Computational and mathematical models are gradually being used to help us understand the omics data produced by high-...
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I examine Leonhard Euler’s original solution to the Königsberg bridges problem. Euler’s solution can be interpreted as both an explanation within mathematics and a scientific explanation using mathematics. At the level of pure mathematics, Euler proposes three different solutions to the Königsberg problem. The differences between these solutions can be fruitfully explicated in terms of explanat...
متن کاملMathematical modeling of cancer cell invasion of tissue: biological insight from mathematical analysis and computational simulation.
The ability of cancer cells to break out of tissue compartments and invade locally gives solid tumours a defining deadly characteristic. One of the first steps of invasion is the remodelling of the surrounding tissue or extracellular matrix (ECM) and a major part of this process is the over-expression of proteolytic enzymes, such as the urokinase-type plasminogen activator (uPA) and matrix meta...
متن کاملBiological Explanations, Realism, Ontology, and Categories
Extended review of: Processes of Life: Essays in the philosophy of biology John Dupré, Oxford University Press, Oxford, 2012, pp. 350, Price £30.00, CA$57.00, US$55.00, Hardback, ISBN-13: 9780199691982
متن کاملPrinciples Used to Evaluate Mathematical Explanations
Mathematics is critical for making sense of the world. Yet, little is known about how people evaluate mathematical explanations. Here, we use an explanatory reasoning task to investigate the intuitive structure of mathematics. We show that people evaluate arithmetic explanations by building mental proofs over the conceptual structure of intuitive arithmetic, evaluating those proofs using criter...
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ژورنال
عنوان ژورنال: Heredity
سال: 2005
ISSN: 0018-067X,1365-2540
DOI: 10.1038/sj.hdy.6800630